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Journal: mSystems
Article Title: Distinct properties of human pathogenic Candida species revealed by systematic comparative phenotypic screening of clinical isolates
doi: 10.1128/msystems.00786-25
Figure Lengend Snippet: High-throughput phenotypic analysis. Screening steps ( A ). Pipetting steps were performed using a liquid handling robot. Strains were cultivated in 96-well microplates with optical density readings (600 nm) in regular intervals. Data analysis and curve fitting steps were performed in R (tidyverse, FactoMineR, growthcurver) and further with PCA and hierarchical clustering. Density plot of growth rates of clinical C. glabrata isolates under ( B ) different temperatures and ( C ) different levels of osmotic stress. Population spread was determined by calculating mean absolute deviation for each condition ( D ).
Article Snippet: The cell suspension was then dispensed into
Techniques: High Throughput Screening Assay